Characterization of antimicrobial resistance in Klebsiella pneumoniae blood cultures from ICU patients at Hospital de Méderi and search for biotechnological alternatives for its control.

Klebsiella pneumoniae is an enterobacterium that has developed a high rate of resistance to antibiotics, due to the acquisition of molecular mechanisms. Globally, it causes 24% of healthcare-associated infections, in Colombia 15% to 19.1%; with a reported attributed mortality rate ranging from 27% to 66%. It emphasizes that the usual diagnoses of resistance of this bacterium do not allow to determine the circulating clones within the institutions and correctly identify the patterns of resistance of KPC, or pathogenicity, which is an indispensable step in the process to design or strengthen new strategies aimed at the control of this microorganism, where they can even be applied, New technologies such as the use of bacteriophages for infection management.