Results and Challenges in the Surgical Treatment of Klatskin Tumor: Case Series in a High-Complexity Hospital in Bogotá

Introduction: Klatskin tumor, also known as hilar cholangiocarcinoma, poses a clinical and therapeutic challenge due to its low incidence, late presentation, and aggressiveness. Worldwide, it accounts for 2% of primary liver tumors, being the second most common after hepatocellular carcinoma. This type of cancer primarily affects men and is associated with high mortality, with an average survival of 40 months in early stages treated surgically and 12 months in advanced cases managed with chemotherapy.

Methodology: A descriptive case series study will be conducted to characterize the population of patients diagnosed with Klatskin tumor who underwent bile duct resection and reconstruction from January 2013 to December 2024. Demographic, clinical, perioperative, and surgical outcomes will be detailed. Variables will be
analyzed using descriptive statistical methods, including absolute and relative frequencies or measures of central tendency and dispersion.

To describe the clinical characteristics and therapeutic approach in patients with Klatskin tumor who underwent bile duct resection and reconstruction at Hospital Universitario Mayor Méderi between 2013 and 2024.

The study aims to identify the clinical and surgical characteristics, as well as postoperative outcomes, both clinical and oncological, of patients undergoing Klatskin tumor resection. This will help establish the most appropriate surgical approach, characterize complication and morbidity-mortality rates, and evaluate postoperative results, contributing to the optimization of comprehensive management for this pathology