Understanding the etiology of human gallstone disease via microbiome analysis of patients from Colombia and in silico mining of global data

  • Quintero, Gustavo A. (PI)
  • Vargas-Barato, Felipe (PI)
  • Dingsdag, Simon (CoI)
  • Ramirez, Juan David (CoI)
  • Chaparro, Henry Mauricio (CoI)
  • Keatinge Clay, Oliver (CoI)
  • Girón Arango, Felipe (CoI)
  • Rey-Chaves, Carlos (CoI)
  • Gonzalez, Felipe (CoI)

Project Details


Despite the high worldwide prevalence of gallstone disease, the role of the biliary microbiota in gallstone pathogenesis remains obscure. Next-generation sequencing offers advantages for systematically understanding the human microbiota. Whole-metagenome shotgun (WMS) sequencing and 16S rRNA sequencing on bile samples, such as described, should contribute to characterizing and understanding microbiological component(s) of the etiology of gallstone disease, and to its treatment and prevention.
Short titleMicrobioma
Effective start/end date10/04/1924/04/23

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being


  • Gallbladder disease
  • cholelithiasis
  • gallstones
  • microbiome
  • microbiota
  • metagenomics
  • metatranscriptomics
  • dysbiosis
  • susceptibility
  • biliary system


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