Disparities in stroke type and vascular risk factors between 2 hispanic populations in Miami and Mexico City

Jose G. Romano, Antonio Arauz, Sebastian Koch, Chuanhui Dong, Juan M. Marquez, Carol Artigas, Marlon Merlos, Bernardo Hernandez, Luis F. Roa, Tatjana Rundek, Ralph L. Sacco

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Background: The heterogeneous nature and determinants of stroke among different Hispanic groups was examined by comparing hospitalized Hispanic stroke patients in Miami, where the Hispanic population is largely of Caribbean origin, to a Mestizo population in Mexico City. Methods: Consecutive Hispanic patients who were admitted with stroke or transient ischemic attack (TIA) and included in the prospective stroke registries of 2 tertiary care teaching hospitals were studied. Demographic factors, stroke subtypes, vascular risk factors, stroke severity, and outcomes were compared. Vascular risk factor definitions were standardized. Results: A total of 928 patients (520 Mexicans and 408 Miami Hispanics) were analyzed. Mexicans were younger, with a greater proportion of women. More cerebral venous thromboses (CVTs) were admitted in Mexico, while TIA and stroke mimics were more commonly admitted in Miami; cardioembolic strokes were more commonly ascertained in Miami, and more cryptogenic strokes in Mexico. Stroke severity was similar for intracerebral hemorrhages, but more severe ischemic strokes and CVTs were included in the Mexican registry. Outcome at 1 and 3 months was similar in both registries after adjusting for age and baseline stroke severity. After adjusting for age and sex, hypertension, dyslipidemia, and atrial fibrillation were more frequent, and diabetes mellitus was less frequent, among Miami Hispanics compared to Mexicans. Conclusions: We found significant differences in the frequency of hypertension, diabetes, dyslipidemia, and atrial fibrillation in Miami Hispanics and Mexican stroke patients, highlighting the heterogeneity of the Hispanic ethnic group. Future studies are needed to clarify the relative contribution of genetic and environmental disparities amongst Mexican and Caribbean Hispanic stroke patients.

Original languageEnglish
Pages (from-to)828-833
Number of pages6
JournalJournal of Stroke and Cerebrovascular Diseases
Issue number6
StatePublished - Aug 2013
Externally publishedYes


  • Hispanics
  • risk factors
  • stroke
  • stroke subtypes


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