TY - JOUR
T1 - Eritrocitosis secundaria a hipoxemia en neumopatías crónicas
T2 - De la reología a la práctica clínica
AU - Galindo, Javier Leonardo
AU - Granados, Carlos Eduardo
AU - García-Herreros, Plutarco
AU - Saavedra, Alfredo
AU - Sánchez, Edgar Alberto
N1 - Publisher Copyright:
© 2016, Universidad Nacional de Colombia. All rights reserved.
PY - 2016
Y1 - 2016
N2 - Erythrocytosis is a rare condition in chronic lung diseases associated to hipoxemia. It’s proper clinical and pathophysiological approach is not very well known. Although erythrocytosis is a compensatory response against hypoxemia, its effects on microcirculation may affect cardiovascular parameters with symptomatic disrepair in patients with this disease. Correction of erythrocytosis through phlebotomy may be a useful therapeutic approach, but there is no clearness about its indication considering the current evidence available; likewise, there are concerns about adverse outcomes that could be generated with its use in rheology and ferrokinetics. It is also unknown the relevance of phlebotomy with regard to the apparent benign prognosis of patients presenting with erythrocytosis in chronic lung diseases. With the scarce current information it is necessary to expand the research on issues related to erythrocytosis due hypoxemia.
AB - Erythrocytosis is a rare condition in chronic lung diseases associated to hipoxemia. It’s proper clinical and pathophysiological approach is not very well known. Although erythrocytosis is a compensatory response against hypoxemia, its effects on microcirculation may affect cardiovascular parameters with symptomatic disrepair in patients with this disease. Correction of erythrocytosis through phlebotomy may be a useful therapeutic approach, but there is no clearness about its indication considering the current evidence available; likewise, there are concerns about adverse outcomes that could be generated with its use in rheology and ferrokinetics. It is also unknown the relevance of phlebotomy with regard to the apparent benign prognosis of patients presenting with erythrocytosis in chronic lung diseases. With the scarce current information it is necessary to expand the research on issues related to erythrocytosis due hypoxemia.
KW - Lung Diseases
KW - Microcirculation
KW - Phlebotomy (MeSH)
KW - Polycythemia
KW - Rheology
UR - http://www.scopus.com/inward/record.url?scp=84979953379&partnerID=8YFLogxK
U2 - 10.15446/revfacmed.v64n2.52489
DO - 10.15446/revfacmed.v64n2.52489
M3 - Artículo de revisión
AN - SCOPUS:84979953379
SN - 0120-0011
VL - 64
SP - 309
EP - 317
JO - Revista Facultad de Medicina
JF - Revista Facultad de Medicina
IS - 2
ER -