Abstract
Granulomatosis with Poliangeitis or Wegner's granulomatosis has an incidence of 5-10 cases per million of habitants and only 2-11% of cases present manifestations in the central nervous system. There are no standardized diagnostic criteria, however, clinical suspicion, positive serology for ANCA'S, histological evidence of necrotizing vasculitis, necrotizing glomerulonephritis or granulomatous inflammation of organs such as skin, lung or kidney, may suggest this pathology. Neurosurgery is a diagnostic and therapeutic option and could be a possibility in those cases in which the lesions are in accessible areas and have low risk of generating comorbidities. We present the case of a 39-year-old female patient with granulomatosis and polyangiitis with involvement in the posterior fossa. After surgical management, it presents meningeal infection. Additionally, we conducted a review of the pathology.
Translated title of the contribution | Granulomatosis with polyangeitis in posterior fosa. Report of a case |
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Original language | German |
Pages (from-to) | 191-197 |
Number of pages | 7 |
Journal | Revista Chilena de Neuro-Psiquiatria |
Volume | 58 |
Issue number | 2 |
DOIs | |
State | Published - Jun 2020 |
Keywords
- Antibodies
- Antineutrophil Cytoplasmic
- Granulomatosis with Polyangiitis
- Neurologic Manifestations
- Neurosurgery
- Wegener Granulomatosis