TY - JOUR
T1 - Guillain-Barré syndrome associated with SARS-CoV-2 infection: A case series from 4 Colombian cities during the pandemic
T2 - A case series from 4 Colombian cities during the pandemic
AU - Cerón Blanco, N.
AU - Rodríguez Quintana, J. H.
AU - Valencia Mendoza, M. C.
AU - Forero Botero, C. A.
AU - Rodríguez, L. C.
AU - Carrillo Villa, S.
AU - Gómez Mazuera, A. M.
AU - Angarita Díaz, J. A.
AU - Uribe García, B.
AU - Bermúdez Riveros, C. C.
AU - Alban, J.
N1 - Publisher Copyright:
© 2022 Sociedad Española de Neurología
PY - 2022/10/1
Y1 - 2022/10/1
N2 - SARS-CoV-2 infection has been associated with multiple neurological manifestations. One such manifestation, which has been described since the early stages of the COVID-19 pandemic and is relevant for current neurological practice, is Guillain-Barré syndrome (GBS). The literature describes neurotoxic mechanisms of the virus itself and the possible pathways by which it may affect the peripheral nerves in experimental studies; however, we still lack information on the mechanisms causing the immune response that gives rise to GBS in the context of SARS-CoV-2 infection. Colombia is one of the Latin American countries worst affected by the pandemic, with the third-highest number of cases in the region; thus, it is essential to recognise GBS, as this potential postinfectious complication may severely compromise the patient's functional status in the absence of timely diagnosis and treatment. We present a series of 12 cases of GBS associated with SARS-CoV-2 infection from hospitals in 4 different Colombian cities and describe the clinical presentation, laboratory and electrophysiological study findings, and treatment.
AB - SARS-CoV-2 infection has been associated with multiple neurological manifestations. One such manifestation, which has been described since the early stages of the COVID-19 pandemic and is relevant for current neurological practice, is Guillain-Barré syndrome (GBS). The literature describes neurotoxic mechanisms of the virus itself and the possible pathways by which it may affect the peripheral nerves in experimental studies; however, we still lack information on the mechanisms causing the immune response that gives rise to GBS in the context of SARS-CoV-2 infection. Colombia is one of the Latin American countries worst affected by the pandemic, with the third-highest number of cases in the region; thus, it is essential to recognise GBS, as this potential postinfectious complication may severely compromise the patient's functional status in the absence of timely diagnosis and treatment. We present a series of 12 cases of GBS associated with SARS-CoV-2 infection from hospitals in 4 different Colombian cities and describe the clinical presentation, laboratory and electrophysiological study findings, and treatment.
KW - Acute polyneuropathy
KW - Coronavirus
KW - Guillain-Barré syndrome
KW - Immunoglobulin
KW - SARS-CoV-2
KW - Weakness
UR - http://www.scopus.com/inward/record.url?scp=85135907169&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/d3e8c8c1-9f96-3a05-bab9-c18e1eee4a40/
U2 - 10.1016/j.neurop.2022.06.004
DO - 10.1016/j.neurop.2022.06.004
M3 - Artículo
AN - SCOPUS:85135907169
SN - 2667-0496
VL - 2
SP - 232
EP - 239
JO - Neurology Perspectives
JF - Neurology Perspectives
IS - 4
ER -