Lymphoproliferative lung disorders: A radiologic-pathologic overview. part ii: Neoplastic disorders

Carlos S. Restrepo, Jorge Carrillo, Melissa Rosado de Christenson, Paulina Ojeda Leon, Aura Lucia Rivera, Micheal N. Koss

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Lymphoproliferative pulmonary neoplasms can occur as primary pulmonary lymphomas or because of secondary pulmonary involvement. Neoplastic disorders may be difficult to differentiate from reactive pulmonary lymphoproliferative disorders, and immunohistochemical evaluation is often required to differentiate the 2 types of lesions.Neoplastic lymphoproliferative disorders are monoclonal lesions. Most affected patients present with systemic complaints, and imaging findings typically include nodules, masses, and lymphadenopathy.Primary pulmonary lymphomas are rare and account for less than 4% of the lymphomas that arise in extranodal sites. Secondary pulmonary lymphomas can affect the lung via hematogenous dissemination or by secondary involvement from tumor in adjacent or contiguous sites. Neoplastic lymphoproliferative lesions also include leukemia and plasma cell neoplasms. Posttransplantation lymphoproliferative disorders constitute a special type of lymphoid proliferation occurring in the setting of the chronic immunosuppression required for solid organ and bone marrow transplantation.

Original languageEnglish
Pages (from-to)535-549
Number of pages15
JournalSeminars in Ultrasound, CT and MRI
Issue number6
StatePublished - Dec 2013


Dive into the research topics of 'Lymphoproliferative lung disorders: A radiologic-pathologic overview. part ii: Neoplastic disorders'. Together they form a unique fingerprint.

Cite this