Lymphoproliferative Lung Disorders: A Radiologic-Pathologic Overview. Part I: Reactive disorders

Jorge Carrillo, Carlos S. Restrepo, Melissa Rosado de Christenson, Paulina Ojeda Leon, Aura Lucia Rivera, Micheal N. Koss

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Lymphoid tissue is a normal component of the lung and manifests as intrapulmonary lymph nodes, bronchus-associated lymphoid tissue (BALT), peripheral lymphocytic aggregates, solitary lymphocytes, and phagocytic cells. Pulmonary lymphoid lesions are thought to develop as a consequence of anomalous stimulation and response of the bronchus-associated lymphoid tissue and manifests as a spectrum of lymphoproliferative disorders that may be reactive or neoplastic. Reactive disorders are polyclonal abnormalities and include nodular lymphoid hyperplasia, lymphocytic interstitial pneumonia, follicular bronchiolitis, angiofollicular hyperplasia, and enlarged intrapulmonary lymph nodes. Affected patients are often asymptomatic. Imaging findings include focal nodules, diffuse bilateral centrilobular nodules, and hilar or mediastinal masses.

Original languageEnglish
Pages (from-to)525-534
Number of pages10
JournalSeminars in Ultrasound, CT and MRI
Issue number6
StatePublished - Dec 2013


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