Postoperative outcomes of minimally invasive adrenalectomy: do body mass index and tumor size matter? A single-center experience

Felipe Girón, Carlos Eduardo Rey Chaves, Lina Rodríguez, Roberto Javier Rueda-Esteban, Ricardo E. Núñez-Rocha, Sara Toledo, Danny Conde, Juan David Hernández, Marco Vanegas, Ricardo Nassar

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Background: Since Gagner performed the first laparoscopic adrenalectomy in 1992, laparoscopy has become the gold-standard procedure in the treatment of adrenal surgical diseases. A review of the literature indicates that the rate of intra- and postoperative complications are not negligible. This study aims to describe the single-center experience of adrenalectomies; and explore the associations between body mass index (BMI) and tumor volume in main postoperative outcomes. Methods: Retrospective observational study with a prospective database in which we described patients who underwent adrenalectomy between January 2015 and December 2020. Operative time, intraoperative blood loss, conversion rate, complications, length of hospital stay, and comparison of the number of antihypertensive drugs used before and after surgery were analyzed. Analysis of BMI and tumor volume with postoperative outcomes such as anti-hypertensive change (AHC) in drug usage and pre-operative conditions were performed. Results: Forty-five adrenalectomies were performed, and all of them were carried out laparoscopically. Four were performed as a robot-assisted laparoscopy approach. Nineteen were women and 26 were men. Mean age was 54.9 ± 13.8 years. Mean tumor volume was 95.698 mm3 (3.75–1010.87). Mean operative time was shorter in right tumors (2.64 ± 0.75 h) than in left tumors (3.33 ± 2.73 h). Pearson correlation was performed to assess the relationship between BMI and AHC showing a direct relationship between increased BMI and higher change in anti-hypertensive drug usage at postoperative period r(45) = 0.92, p > 0.05 CI 95%. Higher tumor volume showed a longer operative time, r(45) = 0.6 (p = 0.000 CI 95%). Conclusions: Obese patients could have an increased impact with surgery with an increased change in postoperative anti-hypertensive management. Tumor volume is associated with increased operative time and blood loss, our data suggest that it could be associated with increased rates of morbidity. However, further prospective studies with larger sample sizes are needed to validate our results.

Original languageEnglish
Article number280
Pages (from-to)280
JournalBMC Surgery
Issue number1
StatePublished - Dec 2022
Externally publishedYes


  • Adrenalectomy
  • Hypertension
  • Laparoscopic
  • Outcomes
  • Robot-assisted
  • Body Mass Index
  • Length of Stay
  • Prospective Studies
  • Adrenal Gland Neoplasms/pathology
  • Humans
  • Middle Aged
  • Adrenalectomy/methods
  • Laparoscopy/methods
  • Postoperative Period
  • Postoperative Complications/etiology
  • Male
  • Blood Loss, Surgical
  • Observational Studies as Topic
  • Adult
  • Female
  • Aged
  • Retrospective Studies
  • Antihypertensive Agents


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