TY - JOUR
T1 - Prevalence of Mild Cognitive Impairment in Southern Regions of Colombia
AU - Bonilla-Santos, Jasmin
AU - González-Hernández, Alfredis
AU - Cala-Martínez, Dorian Yisela
AU - Gómez-Morales, Duván Fernando
AU - Calceto-Garavito, Laura Natalia
AU - Forero-Aldana, Arnulfo Eduardo
AU - González-Montealegre, Rodrigo Alberto
AU - Cardona Cumaco, Yeing Alexandra
AU - Rojas-Bernal, Luz Angela
AU - Zabaleta-Orozco, Mario Alberto
AU - Parra, Mario Alfredo
N1 - Publisher Copyright:
© 2023 - The authors. Published by IOS Press.
PY - 2023/12/29
Y1 - 2023/12/29
N2 - Background: Recent reports suggest that by 2050 there will be an increase of around 310% of cases affected by dementia in Latin American countries. A previous study in a Southern region reported one of the highest prevalences of dementia in Latin America. Objective: To investigate the prevalence of mild cognitive impairment associated with low education, rurality, and demographic characteristics. Methods: A cross-sectional study recruited a community-dwelling sample of 823 adults from rural and urban areas of two Southern provinces of Colombia from 2020-2022. Participants were assessed with a neuropsychological protocol validated in Colombia. To obtain general and region-specific prevalence rates, age, sex, schooling, and socioeconomic level were considered and controlled for. Results: Most of the participants reported low education and socioeconomic level, the participation of women was higher. It was determined that the prevalence of mild cognitive impairment (MCI) was 53.6%, with 56.6% in the province of Caquetá followed by 51.9% in the province of Huila. The amnestic MCI represented 42.6%, the amnestic multi-domain was 39%, the non-amnestic 16.55%, and the non-amnestic multi-domain 1.81%. Our participants reported comorbidities such as diabetes and hypertension. We also observed a relationship between exposure to pesticides and MCI. Conclusions: We observed one of the highest prevalences of MCI in Latin America reported to date. Variables such as age, gender, and education proved risk factors for MCI in the explored regions. Our findings are very much in line with recent studies that highlight the influence of non-canonical risk factors of dementia in underrepresented countries from Latin America.
AB - Background: Recent reports suggest that by 2050 there will be an increase of around 310% of cases affected by dementia in Latin American countries. A previous study in a Southern region reported one of the highest prevalences of dementia in Latin America. Objective: To investigate the prevalence of mild cognitive impairment associated with low education, rurality, and demographic characteristics. Methods: A cross-sectional study recruited a community-dwelling sample of 823 adults from rural and urban areas of two Southern provinces of Colombia from 2020-2022. Participants were assessed with a neuropsychological protocol validated in Colombia. To obtain general and region-specific prevalence rates, age, sex, schooling, and socioeconomic level were considered and controlled for. Results: Most of the participants reported low education and socioeconomic level, the participation of women was higher. It was determined that the prevalence of mild cognitive impairment (MCI) was 53.6%, with 56.6% in the province of Caquetá followed by 51.9% in the province of Huila. The amnestic MCI represented 42.6%, the amnestic multi-domain was 39%, the non-amnestic 16.55%, and the non-amnestic multi-domain 1.81%. Our participants reported comorbidities such as diabetes and hypertension. We also observed a relationship between exposure to pesticides and MCI. Conclusions: We observed one of the highest prevalences of MCI in Latin America reported to date. Variables such as age, gender, and education proved risk factors for MCI in the explored regions. Our findings are very much in line with recent studies that highlight the influence of non-canonical risk factors of dementia in underrepresented countries from Latin America.
KW - Alzheimer's disease
KW - epidemiology
KW - mild cognitive impairment
KW - pesticides
KW - prevalence
UR - http://www.scopus.com/inward/record.url?scp=85182357003&partnerID=8YFLogxK
U2 - 10.3233/ADR-230041
DO - 10.3233/ADR-230041
M3 - Artículo
AN - SCOPUS:85182357003
SN - 2542-4823
VL - 7
SP - 1455
EP - 1464
JO - Journal of Alzheimer's Disease Reports
JF - Journal of Alzheimer's Disease Reports
IS - 1
ER -