TY - JOUR
T1 - Efficacy of Nonpharmacological Interventions in Cognitive Impairment
T2 - Systematic Review And Network Meta-Analysis
AU - Venegas-Sanabria, Luis Carlos
AU - Cavero‑Redondo, Iván
AU - Lorenzo-Garcia, Patricia
AU - Sánchez-Vanegas, Guillermo
AU - Álvarez-Bueno, Celia
N1 - Publisher Copyright:
© 2024 The Authors
PY - 2024
Y1 - 2024
N2 - Introduction: There is currently no known cure for cognitive impairment, which highlights the need to explore other ways of managing this condition. This topic has recently become an area of active research. However, the availability of nonpharmacological options poses a challenge when trying to determine the best treatment for improving cognitive function. Methods: We conducted a systematic review and a Bayesian network meta-analysis to compare the effects of nonpharmacological interventions on global cognition in patients with mild cognitive impairment and dementia. The nonpharmacological interventions were classified as aerobic exercise, strength exercise, multicomponent physical exercise, other physical exercises, tai chi, mind-body exercises, traditional cognitive rehabilitation, computer-based cognitive rehabilitation, occupational therapy, music therapy, physical-cognitive rehabilitation, and reminiscence therapy. Results: Physical-cognitive rehabilitation emerged as the most effective nonpharmacological intervention for enhancing global cognition in patients with unspecified cognitive impairment and dementia, whereas occupational therapy focused on dual-task interventions was found to be the most effective nonpharmacological intervention for mild cognitive impairment. Conclusion: These results underscore the importance of adopting a dual approach to managing cognitive impairment, integrating both cognitive and physical rehabilitation within the same intervention.
AB - Introduction: There is currently no known cure for cognitive impairment, which highlights the need to explore other ways of managing this condition. This topic has recently become an area of active research. However, the availability of nonpharmacological options poses a challenge when trying to determine the best treatment for improving cognitive function. Methods: We conducted a systematic review and a Bayesian network meta-analysis to compare the effects of nonpharmacological interventions on global cognition in patients with mild cognitive impairment and dementia. The nonpharmacological interventions were classified as aerobic exercise, strength exercise, multicomponent physical exercise, other physical exercises, tai chi, mind-body exercises, traditional cognitive rehabilitation, computer-based cognitive rehabilitation, occupational therapy, music therapy, physical-cognitive rehabilitation, and reminiscence therapy. Results: Physical-cognitive rehabilitation emerged as the most effective nonpharmacological intervention for enhancing global cognition in patients with unspecified cognitive impairment and dementia, whereas occupational therapy focused on dual-task interventions was found to be the most effective nonpharmacological intervention for mild cognitive impairment. Conclusion: These results underscore the importance of adopting a dual approach to managing cognitive impairment, integrating both cognitive and physical rehabilitation within the same intervention.
KW - dementia
KW - Global cognition
KW - mild cognitive impairment
KW - rehabilitation
KW - Global cognition
KW - rehabilitation
KW - mild cognitive impairment
UR - http://www.scopus.com/inward/record.url?scp=85199075143&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/c87cef11-7620-3527-bcc9-178fae487cd4/
U2 - 10.1016/j.jagp.2024.06.012
DO - 10.1016/j.jagp.2024.06.012
M3 - Artículo
AN - SCOPUS:85199075143
SN - 1064-7481
JO - American Journal of Geriatric Psychiatry
JF - American Journal of Geriatric Psychiatry
ER -